With top-ranked Kentucky losing on Tuesday, the door is now wide open for several college basketball teams to claim to "we're #1." One of those teams is the Villanova Wildcats, currently ranked third in the country. They will host Big East rival Notre Dame on Wednesday at the Wachovia Center in Philadelphia. BetUS Sportsbook has opened the line at -11 and the total at 165.

'Nova has done quite well for its backers this season, going 12-4 ATS as a favorite and 2-0 ATS as an underdog or pick. When laying double digits, they've covered four straight, including lines of -28 vs. Fordham and -28.5 vs. Delaware. In Big East play, they downed DePaul 99-72 as 18.5-point chalk and just last week waxed Rutgers 94-68 as 13.5-point road favorties. Overall, the Wildcats have a point differential of 14.5 points per game this season and a record of 18-1. Their only loss came at Temple on December 13th.

An 11th straight victory would give the program its best start ever. No Villanova team has won 11 straight games in nearly four years. G Scottie Reynolds leads a three-guard lineup and is leading the team in scoring at 18.7 PPG. In Big East play, that average jumps to 21.4 PPG on 58.7% shooting. Twenty-four more points and he'll have 2,000 for his career. Reynolds had 19 points in the team's 81-71 win over St. John's on Saturday, a game the Wildcats covered as seven-point favorites. It was their fourth consecutive ATS win.

This is the second time this season Villanova will be playing at the Wachovia Center. On January 17th, they beat Georgetown 82-77 to start the four game stretch of ATS victories and improve their mark to 16-8 straight up their last 24 games played at the Wachovia Center.

Another contributing factor to the high line is how bad Notre Dame has been on the road the past couple seasons. This year, the Irish are just 2-3 SU away from South Bend, including conference losses to UConn and Cincinnati. They are also 1-2 vs. Top 10 teams this season after losing at home to Syracuse last Monday as 2.5-point underdogs.

Villanova won the only meeting between the schools last season, 77-60, in South Bend.